October 2024

PDH complex and the TCA cycle- NBME style questions set-2

Practice questions, USMLE styled question bank /

1. The cytosolic isoform of which of the following TCA cycle enzymes requires NADP⁺ as a coenzyme, which can be utilized in the reduced state for reductive biosynthesis? A. Aconitase B. Citrate Synthase C. Isocitrate Dehydrogenase D. Malate Dehydrogenase E. Succinate Dehydrogenase The correct answer is C: Isocitrate Dehydrogenase: The cytosolic isoform of isocitrate dehydrogenase […]

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PDH complex and the TCA cycle- NBME style questions set-1

Practice questions, USMLE styled question bank /

1. A 24-year-old woman presents with diarrhea, dysphagia, jaundice, and white transverse lines on her fingernails (Mee’s lines). She is diagnosed with arsenic poisoning. Arsenic poisoning inhibits which of the following enzymes? A. Citrate synthase B. Isocitrate dehydrogenase C. Malate dehydrogenase D. Succinate dehydrogenase E. α-Keto glutarate dehydrogenase complex Correct answer: E. α-Keto glutarate dehydrogenase

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Glycolysis Review- NBME style questions with complete explanations

All, Quick Revision Series, USMLE styled question bank /

Q.1 Identify the Phosphoester that is predominantly encountered in erythrocytes and plays a vital role in modulating the oxygen-binding affinity of hemoglobin: A. 1,3-Bisphosphoglycerate B. 2,3-Bisphosphoglycerate C. Fructose 1,6-bisphosphate D. Fructose 6-phosphate E. Glucose 6-phosphate The correct answer is B. 2,3-Bisphosphoglycerate (2,3-BPG): 2,3-Bisphosphoglycerate is a negatively charged molecule found in high concentrations within erythrocytes. 2,3-BPG

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NBME-Style Case-Based Questions on the regulation of glycolysis with explanations

Quick Revision Series, USMLE styled question bank /

Question 1: A 25-year-old man runs a marathon. After 20 miles, his muscle cells are relying heavily on glycolysis for energy production. Which of the following changes is most likely increasing the rate of glycolysis in his muscles? A. Accumulation of alanine B. Decreased availability of glucose C. Decreased oxygen levels D. Increased AMP concentration

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Summary of Regulation of Glycolysis

Quick Revision Series /

Glycolysis is the metabolic pathway that converts glucose into pyruvate, generating ATP and NADH in the process. It occurs in the cytoplasm of cells and is essential for energy production. Glycolysis is regulated at multiple levels to match energy demand with supply. Modes of Glycolysis Regulation Substrate Concentration The availability of glucose directly influences the

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