Metabolism and significance of Glycine
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November 2024
Biochemistry Challenge- Part 2
With 21 questions, in this section, you’ll explore real-world applications of biochemistry, sharpen your critical thinking, and connect biochemical concepts to clinical insights. Dive in, think deeply, and discover the fascinating intricacies of metabolic pathways. 1. A 35-year-old factory worker is brought to the emergency department after accidental exposure to cyanide fumes. The patient presents
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Biochemistry Challenge- Part 1
Through hypothetical clinical cases and research scenarios, this activity will challenge your understanding of carbohydrate metabolism, amino acid metabolism, oxidative phosphorylation, and enzymes. With 25 questions, in this section, you’ll explore real-world applications of biochemistry, sharpen your critical thinking, and connect biochemical concepts to clinical insights. Dive in, think deeply, and discover the fascinating intricacies
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Explanations of Quiz on Nucleotide Metabolism
1. A 2-year-old child presents to the clinic with failure to thrive and megaloblastic anemia. Laboratory tests reveal elevated urinary orotic acid levels but normal ammonia levels, normal CSF glutamine levels, and normal serum vitamin B12 and folate levels. Which enzyme deficiency is the most likely cause of this child’s condition? A. Adenosine deaminase B.
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Explanations of Quiz on Lipid Metabolism
1. In adipose tissue, through which of the following intermediates can glucose be converted to glycerol-3-phosphate for the esterification of fatty acids to form triglycerides? A. Acetyl CoA B. Dihydroxyacetone phosphate C. Glycerol D. Malate E. Pyruvate Correct Answer: B. Dihydroxyacetone phosphate: Explanation: Dihydroxyacetone phosphate (DHAP), derived from glycolysis, is reduced to glycerol-3-phosphate by the
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Nucleotide metabolism- A Quiz for self-assessment
Dear Students, You are invited to take this quiz, which consists of 25 questions designed to test your understanding of the topic. The entire activity will take approximately 40 minutes to complete. Detailed explanations for all questions will be posted later on the website to help you deepen your knowledge. Happy learning, and good luck! Click the link or
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Fatty acid and Triglyceride metabolism- a quiz for self-assessment
Dear students, This 32-question quiz is designed to help you assess your understanding of key concepts in fatty acid and triglyceride metabolism and identify any gaps in your learning. The entire activity is timed for a maximum of 50 minutes, and you are encouraged to complete it in one sitting. You can attempt the quiz
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Essential Vitamins in Metabolism: Impacts on Fatty Acid, Triglyceride, and Nucleotide Pathways
Table 1: Fatty Acid and Triglyceride Metabolism Vitamin Impaired Reaction Enzyme Affected Consequence Riboflavin (B2) β-oxidation of fatty acids Acyl-CoA dehydrogenase Reduced ATP production from fats Niacin (B3) β-oxidation of fatty acids Hydroxyacyl-CoA dehydrogenase Energy generation from fats reduced Triglyceride synthesis Glycerol-3-phosphate dehydrogenase Impaired triglyceride formation Biotin Fatty acid synthesis Acetyl-CoA carboxylase Disrupted synthesis of
Vitamin Deficiencies and Impairments in Amino Acid Metabolism
Vitamin Impaired Reaction Enzyme Affected Reaction Catalyzed Pathway/Consequence Vitamin B6 (PLP) Transamination of amino acids Aminotransferases (e.g., ALT, AST) Alanine + α-Ketoglutarate ↔ Pyruvate + Glutamate Impaired amino acid catabolism and gluconeogenesis Conversion of glutamate to γ-aminobutyric acid (GABA) Glutamate decarboxylase Glutamate → GABA + CO₂ Impaired neurotransmitter synthesis Conversion of homocysteine to cystathionine
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Vitamin Deficiencies and Impairments in Carbohydrate Metabolism
Vitamin Impaired Reaction Enzyme Affected Reaction Catalyzed Pathway/Consequence Thiamine (B1) Conversion of pyruvate to acetyl-CoA Pyruvate dehydrogenase (E1 component) Pyruvate + CoA + NAD⁺ → Acetyl-CoA + NADH + CO₂ Impaired entry of pyruvate into the TCA cycle, lactic acid buildup Conversion of α-ketoglutarate to succinyl-CoA α-Ketoglutarate dehydrogenase α-Ketoglutarate + NAD⁺ + CoA →
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