Case Study of the Week

Prostaglandin synthesis and the significance of COX-1 and 2 (case study-2)

Case details A 63-year-old female presented to the clinic with recurrent mid-epigastric pain over the last 3 months. She also reported feeling tired and had to increase the amount of ibuprofen needed for the relief of her arthritis.  She reported some relief of epigastric pain shortly after eating, but then the discomfort returned. She had

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α1-Antitrypsin deficiency- a case study (week 1)

Case details A severe form of obstructive lung disease starting with dyspnea and leading progressively towards emphysema was found in several members of the family. One brother had died earlier of lung disease. Blood plasma from his surviving brother and sister showed an abnormally low concentration of α1-Antitrypsin (5.5 μm, normal is 20–48 μm), the

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