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Summary of Amino acid disorders with easy recall mnemonics

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  Disorder Defective Enzyme/Transporter Clinical Picture Mnemonic Phenylketonuria (PKU) Phenylalanine hydroxylase Musty body odor, intellectual disability, seizures, pale skin, eczema Pale kids with Krappy Urine Alkaptonuria Homogentisic acid oxidase Black urine, ochronosis (bluish-black pigmentation in connective tissues), arthritis Black CAP: Cartilage, Arthritis, Pigmentation Maple Syrup Urine Disease (MSUD) Branched-chain α-ketoacid dehydrogenase Sweet-smelling urine, poor feeding, […]

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Glycolysis Review- NBME style questions with complete explanations

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Q.1 Identify the Phosphoester that is predominantly encountered in erythrocytes and plays a vital role in modulating the oxygen-binding affinity of hemoglobin: A. 1,3-Bisphosphoglycerate B. 2,3-Bisphosphoglycerate C. Fructose 1,6-bisphosphate D. Fructose 6-phosphate E. Glucose 6-phosphate The correct answer is B. 2,3-Bisphosphoglycerate (2,3-BPG): 2,3-Bisphosphoglycerate is a negatively charged molecule found in high concentrations within erythrocytes. 2,3-BPG

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Biochemistry-Practice Questions (Problem-based multiple choice questions)

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Biochemistry-Practice Questions (Problem-based multiple choice questions) 1)- Several complexes in the electron transport chain contain non-heme iron. The iron in these complexes is bound tightly to which of the following amino acids? a) Serine b) Tyrosine c) Cysteine d) Methionine e) Glutamine 2)- A 27 –year-old female with epilepsy has been taking Phenytoin to control

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