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Frequently asked subjective questions
Q.1- What are ω6 and ω3 fatty acid ? Give examples in support of your answer and discuss their biological significance.
Q.2- Explain the terms-
a) Saponification
b) Rancidity
c) Lipid Peroxidation
Q.3- Give an example of each of the followings-
a) Cyclic fatty acid
b) Branched-chain fatty acid
c) Trans fatty acid
d) Pentaenoic acid
e) A saturated fatty acid with 20 carbon atoms
Q.4- What is the relationship of the melting point with the degree of unsaturation of fatty acids? What is its biological significance?
Q.5- What are essential fatty acids, discuss the functions and the clinical consequences of their deficiencies?
Q.6- Discuss the structure, functions and clinical significance of cholesterol.
Q.7- Give a brief account of the chemistry and functions of phospholipids.
Q.8- Differentiate between Cerebrosides and Gangliosides, in reference to chemistry, functions and clinical significance of each of them.
Q.9- Give a brief account of a biochemical defect, clinical symptoms, laboratory diagnosis and treatment of the following diseases-
- a) Tay- Sach’s disease
- b) Gaucher disease
- c) Niemann Pick’s disease
Q.10- What is the clinical significance of the Lecithin/ Sphingomyelin (L/S) ratio?
Q.11- Discuss in brief about the sources, functions, and significance of glycerol.
Q.12- Draw a well-labeled diagram of a liposome, discuss its structure and functions.
Q.13- Enumerate the derived lipids and give a detailed account of any two of them.
Q.14- Why do saturated fatty acids have a higher boiling point than the unsaturated fatty acids with the same number of carbon atoms?
Q.15- Give a brief account of esterification of cholesterol by Acyl transferases, differentiate between the activities of each of them.
Q.16- What are phospholipases? Mention the site of action and the biological significance of each of them.
Q.17-Give the components and the biological function of each of the followings-
a) Triglycerides
b) Phosphatidyl Choline
c) Sphingomyelin
d) GM1- Ganglioside
Q.18- Give an account of lipid storage diseases in a tabular manner, mentioning the biochemical defect and clinical manifestations.
Q.19- Write the significance of-
a) Acid number
b) Acetyl number
c) Saponification number
d) Iodine number.
Q.20- Give a brief account of the steps of Prostaglandin synthesis, mention the role of COX inhibitors.
Q.21- What is the biological and clinical significance of prostaglandins?
Q.22- What is the biochemical basis of low dose Aspirin in antithrombotic prophylaxis?
Q.23-Discuss the synthesis of biologically important Leukotrienes and Lipoxins from Arachidonic acid
Q.24-What is the relationship of COX inhibition and gastric ulceration?
Q.25-What is the role played by Prostaglandins in pregnancy?
Q.26-What is the drawback of the usage of prostaglandins as conventional drugs?
Q.27-What is the reason for Aspirin-induced asthma?
Q.28- Differentiate between prostacyclin and Thromboxane.
Q.29- What is the clinical significance of Leukotrienes?
Q.30- What is SRSA? Explain briefly.