Case details The peripheral blood film (figure) of a strictly vegetarian patient suffering from generalized weakness, easy fatigue, sore tongue, and foot drop has been displayed. What might be the diagnosis? Case details Most probably, the patient is suffering from megaloblastic anemia due to cobalamine deficiency. The cause for this anemia is a strict vegetarian […]
A 23 –year- old female was brought for consultation by her mother, who was troubled by her daughter’s continuous fatigue, dizziness, and loss of weight. The patient was 6 feet 2 inches tall and weighed 100 pounds. Further questioning revealed that the young woman had been virtually fasting for four months, hoping to obtain a
Starvation induced metabolic alterations Read More »
Case details A 54- year-old man with Type 1 diabetes is referred to an ophthalmologist for evaluation of developing cataract. Blood chemistry results are shown below: Fasting blood glucose 198 mg/dl Hemoglobin A 15 gm/dl Hemoglobin A1c 10% of total Hb Urine ketones Positive Urine glucose Positive Which of the following enzymes is most strongly
Question of the week Read More »
1-State Chargaff’s rule In DNA molecules, the concentration of deoxyadenosine (A) nucleotides equals that of thymidine (T) nucleotides (A = T), while the concentration of deoxyguanosine (G) nucleotides equals that of deoxycytidine (C) nucleotides (G = C). 2- What is meant by hyperchromicity of denaturation? The conjugated double bonds of purine and pyrimidine derivatives absorb
Molecular Biology- Viva Questions- Set -1 Read More »
Enzyme and pathway Effect of substrate concentration Allosteric Modification/ Feedback Inhibition/Covalent modification Induction/ Repression Clinical Significance Acetyl co A Carboxylase (Fatty acid synthesis) Activity increases during the well-fed state Activity decreases during fasting Activator- Citrate, ATP Acetyl co A Insulin- activates the enzyme by covalent modification of the enzyme (dephosphorylation through stimulating protein phosphatase enzyme) Inhibitors–
Regulatory Mechanisms- Lipid Metabolism (summary Chart) Read More »
Fatty acid metabolism- Animations http://www.wiley.com/legacy/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm http://www.brookscole.com/chemistry_d/templates/student_resources/shared_resources/animations/carnitine/carnitine1.html http://nutrition.jbpub.com/resources/animations.cfm?id=23&debug=0 Cholesterol metabolism- Animations http://www.google.mu/url?sa=t&rct=j&q=cholesterol%20metabolism&source=web&cd=6&ved=0CEgQFjAF&url=http%3A%2F%2Fwww.wiley.com%2Fcollege%2Fboyer%2F0470003790%2Fanimations%2Fcholesterol%2Fcholesterol.htm&ei=Y1u_To6eLpS3hAfBl5yqBA&usg=AFQjCNEnz6PRIRPbutRUAAO5FS-aqAxguQ&cad=rja Lipoprotein metabolism http://www.wiley.com/college/pratt/0471393878/student/animations/lipoproteins/index.html https://www.youtube.com/watch?v=97uiV4RiSAY Atherosclerosis https://www.youtube.com/watch?v=OHE1ig4k64M LDL and HDL cholesterol https://www.youtube.com/watch?v=0U7YHRW5dyc
Lipid metabolism- animations Read More »
Q.- Adenosine triphosphate (ATP) is the energy currency within the cell. Which of the following best describes the type of compound ATP is? A. Phospholipid B. Amino acid C. Nucleotide D. Triacylglycerol E. Oligosaccharide. Details The correct answer is -C- Nucleotide. The nucleotide coenzyme adenosine triphosphate (ATP) is the most important form of chemical energy
ATP- The energy currency within the cell Read More »
Introduction Renal clearance is a measurement to analyze the functions of the kidney. By definition, clearance is the volume of plasma from which the excretion completely removes a substance through the kidney in a given amount of time (usually a minute). For example, the clearance for urea is 75 ml/min. This means that the kidney
Renal clearance- a quick revision Read More »
ATP SYNTHASE ANIMATIONS Click the link below for more animations http://www.wiley.com/college/pratt/0471393878/student/animations/oxidative_phosphorylation/index.html
Animations – ATP synthase complex and electron transport chain Read More »
Case details A 65-year-old man was admitted to the emergency department in an unconscious state. Apparently he had become increasingly depressed after the death of his younger son two months ago. Previously before his death, he had been a moderate drinker, but consumption of alcohol had increased markedly over the last few weeks. He had
Alcohol induced metabolic changes- a case study Read More »
