| Our Biochemistry- Namrata Chhabra

Metabolic disorders- Carbohydrate metabolism

S.N. Process/Pathway affected Disease Major Manifestation 1) Digestion Lactose intolerance Sucrase/Isomaltase deficiency Inability to digest dairy products, bloating, pain- abdomen, diarrhea or constipation, etc. 2) Absorption (SGLT-1or SGLT-2 deficiency) Glucose/Galactose malabsorption Impaired dietary glucose/galactose absorption (SGLT-1), or Renal glycosuria (SGLT-2) 3) Glycolysis Hexokinase or Pyruvate kinase deficiency ( Hemolytic anemia 4) PDH Complex […]

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Biologically important peptides

Quick Revision Series / Namrata Chhabra

A 56-year-old man with long-standing poorly controlled diabetes mellitus visits his primary care physician for a follow up after recent hospitalization. The patient experienced an episode of acute renal failure while in the hospital and his creatinine level rose to 4 mg/dl. Creatinine, a marker of renal function is produced from which of the following

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Novel Coronavirus from China

α1-Antitrypsin deficiency- a case study (week 1)

Case Study of the Week / Namrata Chhabra

Case details A severe form of obstructive lung disease starting with dyspnea and leading progressively towards emphysema was found in several members of the family. One brother had died earlier of lung disease. Blood plasma from his surviving brother and sister showed an abnormally low concentration of α1-Antitrypsin (5.5 μm, normal is 20–48 μm), the

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Question of the week 1

Question of the Week / Namrata Chhabra

A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency given the patients’ diet and symptoms. Which

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Our Biochemistry.com

Announcements / Namrata Chhabra

A website purely based on the description of clinical cases- The highlights of this site are real or constructed clinical problems solved by applying the fundamental concepts of Biochemistry. These introductions are essential prerequisites for arriving at a diagnosis.

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Handbook of Biochemistry Spotting

Reference Books by Namrata Chhabra / Namrata Chhabra

https://www.amazon.com/Handbook-Biochemistry-Spotting-Namrata-Chhabra/dp/9352501438 This book is founded on the concept of problem-based learning. The aim of this book is to get the students of Health and Medical Sciences aware of the basic biochemical principles and to practice these principles in analyzing commonly occurring health-associated problems in terms of their biochemical components. The text, although clinically relevant, is

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A Case Oriented Approach Towards Biochemistry

Reference Books by Namrata Chhabra / Namrata Chhabra

https://www.amazon.com/Case-Oriented-Approach-Towards-Biochemistry/dp/9350901889/ref=sr_1_1?keywords=Case+Oriented+Approach+Towards+Biochemistry&qid=1582308149&sr=8-1 This book summarizes the essentials of Biochemistry with Clinical Correlations. The purpose of this book is to present a clear discussion of Biochemistry in relation to physiological processes occurring at the cellular levels and to cite examples of deviant biochemical processes in different clinical conditions. This book contains evaluations of clinical cases in sections,

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Spot diagnosis

Image Challenge / Namrata Chhabra

A 48-year-old man presents with a short history of severe low backache, loss of weight and diminished appetite. X-Ray skull shows punched out lesions. Serum electrophoresis reveals an abnormal band between the β globulin and the γ globulin region. What is the probable diagnosis? Please check the answer at: Image challenge-1- Answer

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Stress-induced hypocalcemia

USMLE styled question bank / Namrata Chhabra

Case details A 15- year-old boy had numbness and tingling around his mouth and in his fingertips. The problem was intermittent usually occurring during times of great stress. Aside from his problem, he had been in good health. His physical examination was normal, as were his laboratory values, especially his total calcium concentration was 2.5

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