| Our Biochemistry- Namrata Chhabra

Prostaglandin synthesis and the significance of COX-1 and 2 (case study-2)

Case Study of the Week / Namrata Chhabra

Case details A 63-year-old female presented to the clinic with recurrent mid-epigastric pain over the last 3 months. She also reported feeling tired and had to increase the amount of ibuprofen needed for the relief of her arthritis. She reported some relief of epigastric pain shortly after eating, but then the discomfort returned. She had […]

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Image challenge-1- Answer

Image Challenge / Namrata Chhabra

Case discussion The patient is suffering from multiple myeloma. Multiple myelomas represent a malignant proliferation of plasma cells derived from a single clone. The plasma cells in a normal individual are end-stage cells that secrete specific antibodies for a few days and then die. In contrast, the plasma cells in an individual with multiple myeloma

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Clinical significance of SGLT-2

USMLE styled question bank / Namrata Chhabra

A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing

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Answer to the Question of the week -1

Question of the Week / Namrata Chhabra

A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency given the patients’ diet and symptoms. Which

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Practice questions

Practice questions / Namrata Chhabra

Q.1- A 73-year-old woman is transferred to an intensive care unit after she is found to be in septic shock. It is believed that she originally had a urinary tract infection and that the bacteria seeded her bloodstream. The critical care fellow is concerned she may not have an adequate stress response in this situation.

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Practice Questions

Practice questions / Namrata Chhabra

1)- Several complexes in the electron transport chain contain non-heme iron. The iron in these complexes is bound tightly to which of the following amino acids? a) Serine b) Tyrosine c) Cysteine d) Methionine e) Glutamine 2)- A 27 –year-old female with epilepsy has been taking Phenytoin to control her seizures. She is pregnant and

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Metabolic disorders- Carbohydrate metabolism

Quick Revision Series / Namrata Chhabra

S.N. Process/Pathway affected Disease Major Manifestation 1) Digestion Lactose intolerance Sucrase/Isomaltase deficiency Inability to digest dairy products, bloating, pain- abdomen, diarrhea or constipation, etc. 2) Absorption (SGLT-1or SGLT-2 deficiency) Glucose/Galactose malabsorption Impaired dietary glucose/galactose absorption (SGLT-1), or Renal glycosuria (SGLT-2) 3) Glycolysis Hexokinase or Pyruvate kinase deficiency ( Hemolytic anemia 4) PDH Complex

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Biologically important peptides

Quick Revision Series / Namrata Chhabra

A 56-year-old man with long-standing poorly controlled diabetes mellitus visits his primary care physician for a follow up after recent hospitalization. The patient experienced an episode of acute renal failure while in the hospital and his creatinine level rose to 4 mg/dl. Creatinine, a marker of renal function is produced from which of the following

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Novel Coronavirus from China

α1-Antitrypsin deficiency- a case study (week 1)

Case Study of the Week / Namrata Chhabra

Case details A severe form of obstructive lung disease starting with dyspnea and leading progressively towards emphysema was found in several members of the family. One brother had died earlier of lung disease. Blood plasma from his surviving brother and sister showed an abnormally low concentration of α1-Antitrypsin (5.5 μm, normal is 20–48 μm), the

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