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Biological oxidation and Electron Transport Chain (Mcqs) – part-2

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1. Dehydrogenases catalyze the transfer of hydrogen from one substrate to another in a coupled oxidation-reduction reaction.These dehydrogenases are specific for their substrates but often utilize common coenzymes or hydrogen carriers, e.g. NAD+. Which out of the following is not niacin ( NAD+) dependent dehydrogenase? a) Pyruvate dehydrogenase b) Glycerol-3-P dehydrogenase( Mitochondrial ) c) Glyceraldehyde-3-P […]

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Biological oxidation and Electron transport chain (Multiple choice questions) – solved- part-3

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Q.1- Choose a site along the electron transport chain out of the following that is not coupled to ATP synthesis: a) NADH- coenzyme Q (CoQ) reductase b) Succinate-Co Q reductase c) Cytochrome bc1 reductase d) Cytochrome oxidase e) None of the above. Q.2- Choose a statement out of the following that best describes the uncouplers

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Electron transport chain and oxidative phosphorylation- Mcqs (set-1)

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Q.1- All of the following except one are NAD+ requiring enzymes – A. Acyl co A dehydrogenase B. Glyceraldehyde-3-P dehydrogenase C. Pyruvate dehydrogenase complex D. Malate dehydrogenase E. Lactate dehydrogenase Q.2- Which one of the following enzymes catalyzes substrate-level phosphorylation in the TCA cycle A. Malate dehydrogenase B. Succinate Thiokinase C. Succinate dehydrogenase D. Alpha

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Electron transport chain and oxidative phosphorylation- MCQs (Set-2)

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Q.1- If the mitochondria were blocked at the site of NADH oxidation and were treated with succinate as substrate, what would the P: O ratio is? A. Zero B. One less than normally produced by succinate C. Same as that normally produced by succinate D. One more than normally produced by succinate E. Higher than

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Electron Transport Chain – An Overview

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An 18-year-old college student is brought to the emergency room unconscious, with a very high serum alcohol level. Alcohol metabolism can result in high NADH levels. When NADH enters the electron transport chain, which of the following is the correct order in which electron transfer occurs? a) NADH, coenzyme Q, cytochrome c, FMN, O2 b)

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Impaired electron flow through complex II

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A -8-year-old boy is seen by an ophthalmologist for difficulties in seeing in all visual fields as well as slow eye movements. The ophthalmologist finds pigmentary retinopathy and ophthalmoplegia. The child is suspected to have Kearns- Sayre syndrome, a disorder due to a mutation in complex II of ETC. The electron transport from which substance

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Electron transport chain inhibition by Rotenone

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An unskilled worker in a water garden was sent to sweep up a spill of white powder in the storage shed. Later, he was found with labored breathing and convulsions. On further examination, the white powder was identified as rotenone. Respiratory distress is induced by rotenone exposure because it inhibits the complex that catalyzes which

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Reduced state of the respiratory chain carriers (Inhibition of electron transport chain)

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As electrons are received and passed down the transport chain, the electron carriers are first reduced with the acceptance of the electron and then oxidized with loss of the electron. A patient poisoned by which of the following compounds has the most highly reduced state of most of the respiratory chain carriers? A. Antimycin A

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Electrophoresis – A brief review

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Electrophoresis is the movement of charged particles through an electrolyte when subjected to an electric Field- Cations move towards the cathode Anions move towards the anode  By this technique, solutes are separated by their different rates of travel through an electric field. Commonly used in biological analysis, particularly in the separations of proteins, peptides, and nucleic acids  Factors affecting

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