Amino acid metabolism

Glycine, a non-essential amino acid, has vital metabolic roles, including serving as a constituent of collagen, a one-carbon donor, and a precursor for purine nucleotides, bile salts, and heme. Clinically, defects in glycine metabolism can lead to conditions like hyperoxaluria, nonketotic hyperglycinemia, and glycinuria, contributing to significant health implications such as oxalate stone formation and neurological disorders.

"Discover how vitamin deficiencies disrupt amino acid metabolism. This detailed guide explains impaired reactions, enzymes affected, and consequences, emphasizing the biochemical role of B6, B1, B9, B12, and biotin in critical pathways."