Amino acids associated with the TCA cycle and their entry points (with easy mnemonics)

Here’s a table showing the amino acids associated with each intermediate and helpful mnemonics to aid memorization:

Intermediate Amino Acids Associated Mnemonic for Amino Acid Entry Points
Pyruvate Glycine, Alanine, Serine, Cysteine, Threonine, Tryptophan, Hydroxyproline
  • G – Glycine
  • A – Alanine
  • S – Serine
  • C – Cysteine
  • T – Threonine
  • T – Tryptophan
  • H – Hydroxyproline

 

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Acetyl-CoA Leucine, Phenylalanine, Tyrosine, Tryptophan, Isoleucine, Lysine
  • L – Leucine
  • P – Phenylalanine
  • Y – Tyrosine
  • T – Tryptophan
  • I – Isoleucine
  • L – Lysine

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TCA Cycle Intermediate
α-Ketoglutarate Glutamate, Glutamine, Arginine Proline, Histidine,
  • G – Glutamate
  • G – Glutamine
  • A – Arginine
  • P – Proline
  • H – Histidine

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Succinyl-CoA Valine, Isoleucine, Methionine, Threonine
  • V – Valine
  • I – Isoleucine
  • M – Methionine
  • T – Threonine

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Fumarate Phenylalanine, Tyrosine ·        P- Phenylalanine

·        T- Tyrosine

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Oxaloacetate Aspartate, Asparagine A-    Aspartate

A-    Asparagine

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