Library

Summary- Regulation of Major Pathways Of Carbohydrate metabolism

Enzyme Pathway Effect of Substrate Concentration Allosteric Modification/ Feedback Inhibition Induction/Repression Clinical Significance Hexokinase Glycolysis Feedback inhibition by Glucose-6-P – Deficiency causes Hemolytic anemia. Glucokinase Glycolysis Stimulated by a high carbohydrate diet   Activity decreases during fasting – Induced by Insulin Repressed by Glucagon Activity low in Diabetes Mellitus Phosphofructokinase-1 Glycolysis Stimulated by a high

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Hypoglycemia Due To Biotin deficiency

A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes

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Case study- Scurvy (vitamin C deficiency)

Case Details A  4 -year-old boy was brought for consultation for hematuria, edema of lower extremities, and as swollen right leg. He was the 12th born in a poor family, where one previous child died from malnutrition and dehydration in the period of infancy.  The child was fed only with cow’s milk and biscuits. From

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Prostaglandin synthesis and the significance of COX-1 and 2 (case study-2)

Case details A 63-year-old female presented to the clinic with recurrent mid-epigastric pain over the last 3 months. She also reported feeling tired and had to increase the amount of ibuprofen needed for the relief of her arthritis.  She reported some relief of epigastric pain shortly after eating, but then the discomfort returned. She had

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Image challenge-1- Answer

Case discussion The patient is suffering from multiple myeloma. Multiple myelomas represent a malignant proliferation of plasma cells derived from a single clone. The plasma cells in a normal individual are end-stage cells that secrete specific antibodies for a few days and then die. In contrast, the plasma cells in an individual with multiple myeloma

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