Biochemistry quiz 3
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Regulatory Mechanisms- Lipid Metabolism (Summary Chart)
Enzyme Pathway Effect of substrate concentration Allosteric Modification/Feedback Inhibition Induction/ Repression Clinical Significance Acetyl CoA Carboxylase Fatty acid synthesis Activity increases during well-fed state Activity decreases during fasting Activator- Citrate, ATP Acetyl CoA Insulin-by causing de-phosphorylation by stimulating protein phosphatase Inhibitors- Long-chain fatty acids, Epinephrine, Glucagon- via changes in phosphorylation state through c AMP mediated phosphorylation cascade Induced
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Hypoglycemia Due To Biotin deficiency
A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes
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Case study-Folic Acid Deficiency
Case details A 44-year-old man who had lost his job because of absenteeism presented to his physician complaining of loss of appetite, fatigue, muscle weakness, and emotional depression. The physical examination revealed a somewhat enlarged liver that was firm and nodular, and there was a hint of jaundice in the sclerae and a hint of
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Case study- Scurvy (vitamin C deficiency)
Case Details A 4 -year-old boy was brought for consultation for hematuria, edema of lower extremities, and as swollen right leg. He was the 12th born in a poor family, where one previous child died from malnutrition and dehydration in the period of infancy. The child was fed only with cow’s milk and biscuits. From
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Case Study (orlistat induced bleeding)
Case Details A 32-year-old male reported to emergency with active bleeding from the nose. History revealed that he had been on Orlistat for weight reduction for the past two years. He had started Orlistat without the advice of any practitioner and had lost nearly 20 kg of body weight. There was no history of hypertension,
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Case study- Vitamin B2 deficiency
A 45 –year-old male, a known alcoholic from the previous 10 years, reported to the physician for consultation. He complained of the burning of eyes and a sore tongue. There was a history of reduced appetite and mild abdominal discomfort. The examination revealed cracks on the lips and in the corners of the mouth. The
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Image challenge-2
A 54- year-old man complains of an acute onset of unilateral eye pain and a reduction in visual acuity. On physical examination, conjunctival injection (eye redness) and a mild-dilated and non-reactive pupil are observed. Fundoscopic examination reveals the cupping of the optic disc. Recognizing the signs and symptoms of glaucoma, the medication Acetazolamide is administered