A 65-year-old man with a history of type 2 diabetes mellitus is complaining of blurred vision and numbness in his toes. Laboratory results are significant for an increased BUN and creatinine, indicative of renal failure, and high HbA1c, indicative of chronic persistent hyperglycemia. Out of the several mechanisms proposed, one mechanism responsible for hyperglycemia-induced complications […]
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The websites- Biochemistry For Medics- Lecture notes (www.namrata.co) and Biochemistry For Medics (usmle.biochemistryformedics.com) are no more operational. Please don’t feel disappointed if you can’t access those websites. This website “Our biochemistry” is an updated version of both the websites. https://ourbiochemistry.com/ Contact me to get the learning resources of your choice. Thanks, Namrata
Our Biochemistry- an updated version of Biochemistry of medics by Namrata Chhabra Read More »
Can an N95 face mask protect you from catching the new coronavirus? Face masks are reportedly selling out in cities across Asia as concerns over the spread of a deadly new coronavirus grow. China’s National Health Commission has deployed masks to healthcare workers responding to the outbreak, and millions of masks have been sent to residents
Case details A 63-year-old female presented to the clinic with recurrent mid-epigastric pain over the last 3 months. She also reported feeling tired and had to increase the amount of ibuprofen needed for the relief of her arthritis. She reported some relief of epigastric pain shortly after eating, but then the discomfort returned. She had
Prostaglandin synthesis and the significance of COX-1 and 2 (case study-2) Read More »
Case discussion The patient is suffering from multiple myeloma. Multiple myelomas represent a malignant proliferation of plasma cells derived from a single clone. The plasma cells in a normal individual are end-stage cells that secrete specific antibodies for a few days and then die. In contrast, the plasma cells in an individual with multiple myeloma
Image challenge-1- Answer Read More »
A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing
Clinical significance of SGLT-2 Read More »
A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency, given the patient’s diet and symptoms. Which
Answer to the Question of the week -1 Read More »
Q.1- A 73-year-old woman is transferred to an intensive care unit after she is found to be in septic shock. It is believed that she initially had a urinary tract infection and that the bacteria seeded her bloodstream. The critical care fellow is concerned she may not have an adequate stress response in this situation.
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The pathway of protein synthesis is called Translation because the ‘language’ of the nucleotide sequence on the mRNA is translated into the language of the amino acid sequence. The m RNA is translated from its 5’end to its 3’end, producing a protein synthesized from its amino-terminal end to its carboxyl-terminal end. Prokaryotic Translation Components required
Translation- an overview Read More »
Gene regulation is significantly more complex in eukaryotes than in prokaryotes for a number of reasons- 1) Large Genome First, the genome being regulated is significantly larger. The E. coli genome consists of a single, circular chromosome containing 4.6 Mb. This genome encodes approximately 2000 proteins. In comparison, the genome within a human cell contains 23 pairs
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