A 23 –year- old female was brought for consultation by her mother, who was troubled by her daughter’s continuous fatigue, dizziness, and loss of weight. The patient was 6 feet 2 inches tall and weighed 100 pounds. Further questioning revealed that the young woman had been virtually fasting for four months, hoping to obtain a […]
Starvation induced metabolic alterations Read More »
Case details A 54- year-old man with Type 1 diabetes is referred to an ophthalmologist for evaluation of developing cataracts. Blood chemistry results are shown below: Fasting blood glucose 198 mg/dl Hemoglobin A 15 gm/dl Hemoglobin A1c 10% of total Hb Urine ketones Positive Urine glucose Positive Which of the following enzymes is most strongly
Question of the week Read More »
Q.- Adenosine triphosphate (ATP) is the energy currency within the cell. Which of the following best describes the type of compound ATP is? A. Phospholipid B. Amino acid C. Nucleotide D. Triacylglycerol E. Oligosaccharide. Details The correct answer is -C- Nucleotide. The nucleotide coenzyme adenosine triphosphate (ATP) is the most important form of chemical energy
ATP- The energy currency within the cell Read More »
Case details A 5- year-old boy suffered gastroenteritis for two days and was brought to the emergency in a semiconscious state. Blood glucose at the time of admission was 45 mg/dl and his urine was negative for glucose and ketone bodies. Glucose was administered intravenously, and his condition improved within 10 minutes. Subsequent laboratory investigations
Elevated Acyl carnitine compounds and associated hypoglycemia- What is the defect? Read More »
A 65-year-old man with a history of type 2 diabetes mellitus is complaining of blurred vision and numbness in his toes. Laboratory results are significant for an increased BUN and creatinine, indicative of renal failure, and high HbA1c, indicative of chronic persistent hyperglycemia. Of the several proposed mechanisms, one mechanism responsible for hyperglycemia-induced complications in
Question the week-2 (Answer) Read More »
A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the
Impaired TCA cycle enzyme activity in angular stomatitis Read More »
A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes
Hypoglycemia Due To Biotin deficiency Read More »
A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing
Clinical significance of SGLT-2 Read More »
1. The following are all characteristics of the genetic code except: Universal Degenerate Non-overlapping Ambiguous 2. Which of the following statements is not true concerning the role of Aminoacyl t-RNA synthetases: Charging an aminoacyl t-RNA synthetase (loading) with an amino acid is an energetically favorable reaction. For every amino acid, there are several Aminoacyl t-RNA
Translation- Multiple-choice questions Read More »
31- A 47- year-old woman passes out at work and is brought to an emergency room. Her blood sugar is 34 mg/dl (normal >60 mg/dl). She is also tested for C-peptide, which is much higher than normal. What is the possible cause of this woman’s state? a) Anorexia b) High protein diet c) Exogenous administration
Problem Based Multiple Choice Questions (Set-3)- Solved with complete discussion Read More »
