USMLE Content

Amino acid metabolism-Multiple-choice questions (set-1)

Q.1- A 12 -year-old boy develops convulsions. After running an Electroencephalogram(EEG), a neurologist determines that the child has epilepsy. He is started on benzodiazepine, which promotes the activity of GABA. GABA is derived from Glutamate by which of the following reactions? a) Transamination b) Decarboxylation c) Deamination d) Hydroxylation e) Dehydrogenation Q.2- A couple of […]

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Molecular Biology-Multiple-choice questions (set-2)

Q.1- Which statement best describes the ‘semi-conservative replication’ of DNA? A) In each replication cycle, only one of the two DNA strands is replicated B) In each replication cycle, one of the parental strands is conserved C) In each replication cycle, the daughter cells acquire either the parental stands or new stands D) Only half

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Molecular Biology- Multiple-choice questions (set-1)

Q.1- A critical enzyme used directly in the synthesis of dTMP (thymidine) is a) Carbamoyl phosphate b) Aspartate Transcarbamylase c) Dihydrooratase d) Thymidylate synthase Q.2- In which phase of the cell cycle does DNA replication occur? a) G0 b) G1 c) S d) G2 Q.3-A 10-month-old baby boy presents with steatorrhea, recurrent pulmonary infections, GI

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Lipid metabolism- Multiple Choice questions-set-2

1- All except one are true about gastric lipase- a)   Main preduodenal lipase b)   Hydrolyzes triglycerides containing short and medium-chain fatty acids c)   The primary site of hydrolysis is the sn-3ester linkage d)   Optimum pH is 6.0-7.0 2- Pancreatic juice does not contain which of the followings- a)   Bile salts b)   Phospholipase A2 c)   Lipase and colipase d)   Lipoprotein lipase 3- The dietary fats are

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Lipids- Multiple-choice questions-set-3

1. Which of the following are the ketone bodies? a) Acetyl CoA and Propionyl CoA b) Lecithin and Lysolecithin c) Acetoacetate and Beta-hydroxybutyrate d) Pyruvate and lactate e) Succinyl CoA and succinate 2. The enzyme ‘Thiolase’ catalyzes the conversion of: a) 2 Acetyl CoA to Acetoacetyl CoA b) Acetyl CoA to Malonyl CoA c) Fatty

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Fatty Acid Metabolism- Multiple-Choice Questions (Solved)-set-4

Q.1- Glucose can be converted to glycerol-3-P through which of the following intermediates? a) Glycerol b) Dihydroxyacetone phosphate c) Acetyl CoA d) Pyruvate e) Malate. Q.2- Which of the following supplies the 2 carbon units that are added to the elongation of the fatty acid chain? a) Acetyl CoA b) Malonyl CoA c) β- Keto

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Cholesterol-chemistry and metabolism- Multiple-choice questions

1)- Cholesterol is a precursor of all of the following except- a) Taurocholate b) Glycocholate c) Calcitriol d) Corticosteroids e) Calcitonin. 2)- All 27 carbon atoms of cholesterol are derived from- a) Acetyl CoA b) Acetoacetyl CoA c) Propionyl CoA d) Succinyl CoA e) Malonyl CoA 3)- Cytosolic  3-hydroxy-3-methylglutaryl CoA (HMG CoA) is reduced to

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Cholesterol metabolism- Multiple-choice questions

Q.1 – A gall stone that blocked the upper part of the bile duct would cause an increase in which of the following? a) The excretion of fats in the feces b) Formation of chylomicrons c) Excretion of bile salts d) Conjugation of bile acids e) Recycling of bile salts Q.2- An 8-year-old boy presents

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Chemistry of Nucleotides-Multiple-choice questions

1- Which statement best describes Xanthine ? a) It is a direct precursor of Guanine b) It covalently binds to Allopurinol c) It is oxidized to form Uric acid d) It is oxidized to form Hypoxanthine e) It is a substrate rather than a product of the enzyme Xanthine oxidase 2- Methylated heterocyclic bases of

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