1) A 4-month-old boy is being evaluated for seizures, psychomotor retardation, and hypotonia. Workup reveals elevated serum levels of lactate, alanine, pyruvate, and keto acids. Based on the clinical presentation, pyruvate carboxylase activity is measured using fibroblasts from a skin biopsy and is found to be markedly decreased. This enzyme is normally used to directly
Gluconeogenesis- Multiple-choice questions Read More »
1). A patient has chronic obstructive pulmonary disease, and enough oxygen is not reaching her tissues. All of the following are expected except- a) The electron transport chain would be inhibited b) Glycolysis would be activated by a low ATP/ADP ratio c) More than normal amounts of ATP would be synthesized. d) Concentrations of NADH and
Glycolysis- Multiple-choice questions (set-1) Read More »
Q.1- Which of the following is a common compound shared by the TCA and Urea cycles? a) α- Ketoglutarate b) Succinyl CoA c) Oxaloacetate d) Fumarate Q.2-Which of the following is a common nitrogen acceptor for all reactions involving transaminases? a) α- Ketoglutarate b) Pyruvate c) Oxaloacetate d) Acetoacetate Q.3- In a 55- year-old man
Amino Acid Metabolism-Multiple-choice questions (set-2) Read More »
Q.1- A 12 -year-old boy develops convulsions. After running an Electroencephalogram(EEG), a neurologist determines that the child has epilepsy. He is started on benzodiazepine, which promotes the activity of GABA. GABA is derived from Glutamate by which of the following reactions? a) Transamination b) Decarboxylation c) Deamination d) Hydroxylation e) Dehydrogenation Q.2- A couple of
Amino acid metabolism-Multiple-choice questions (set-1) Read More »
Q.1- Which statement best describes the ‘semi-conservative replication’ of DNA? A) In each replication cycle, only one of the two DNA strands is replicated B) In each replication cycle, one of the parental strands is conserved C) In each replication cycle, the daughter cells acquire either the parental stands or new stands D) Only half
Molecular Biology-Multiple-choice questions (set-2) Read More »
Q.1- A critical enzyme used directly in the synthesis of dTMP (thymidine) is a) Carbamoyl phosphate b) Aspartate Transcarbamylase c) Dihydrooratase d) Thymidylate synthase Q.2- In which phase of the cell cycle does DNA replication occur? a) G0 b) G1 c) S d) G2 Q.3-A 10-month-old baby boy presents with steatorrhea, recurrent pulmonary infections, GI
Molecular Biology- Multiple-choice questions (set-1) Read More »
1- All except one are true about gastric lipase- a) Main preduodenal lipase b) Hydrolyzes triglycerides containing short and medium-chain fatty acids c) The primary site of hydrolysis is the sn-3ester linkage d) Optimum pH is 6.0-7.0 2- Pancreatic juice does not contain which of the followings- a) Bile salts b) Phospholipase A2 c) Lipase and colipase d) Lipoprotein lipase 3- The dietary fats are
Lipid metabolism- Multiple Choice questions-set-2 Read More »
1. Which of the following are the ketone bodies? a) Acetyl CoA and Propionyl CoA b) Lecithin and Lysolecithin c) Acetoacetate and Beta-hydroxybutyrate d) Pyruvate and lactate e) Succinyl CoA and succinate 2. The enzyme ‘Thiolase’ catalyzes the conversion of: a) 2 Acetyl CoA to Acetoacetyl CoA b) Acetyl CoA to Malonyl CoA c) Fatty
Lipids- Multiple-choice questions-set-3 Read More »
Q.1- Glucose can be converted to glycerol-3-P through which of the following intermediates? a) Glycerol b) Dihydroxyacetone phosphate c) Acetyl CoA d) Pyruvate e) Malate. Q.2- Which of the following supplies the 2 carbon units that are added to the elongation of the fatty acid chain? a) Acetyl CoA b) Malonyl CoA c) β- Keto
Fatty Acid Metabolism- Multiple-Choice Questions (Solved)-set-4 Read More »
1)- Cholesterol is a precursor of all of the following except- a) Taurocholate b) Glycocholate c) Calcitriol d) Corticosteroids e) Calcitonin. 2)- All 27 carbon atoms of cholesterol are derived from- a) Acetyl CoA b) Acetoacetyl CoA c) Propionyl CoA d) Succinyl CoA e) Malonyl CoA 3)- Cytosolic 3-hydroxy-3-methylglutaryl CoA (HMG CoA) is reduced to
Cholesterol-chemistry and metabolism- Multiple-choice questions Read More »
