Image Challenge

A 25 –year-old women presented, with a history that includes- a) Hepatosplenomegaly with eventual removal of spleen b) Bone and joint pains with several fractures of the femur. c) A liver biopsy that shows wrinkled looking cells with accumulation of Glucosyl ceramide,

Case details The peripheral blood film (figure) of a strictly vegetarian patient suffering from generalized weakness, easy fatigue, sore tongue, and foot drop has been displayed. What might be the diagnosis? Case details Most probably, the patient is suffering from megaloblastic anemia due to cobalamine deficiency. The cause for this anemia is a strict vegetarian

A 54- year-old man complains of an acute onset of unilateral eye pain and a reduction in the visual acuity. On physical examination, conjunctival injection (eye redness) and a mild-dilated and non-reactive pupil are observed. Fundoscopic examination reveals the cupping of the optic disc. Recognizing the signs and symptoms as glaucoma, the medication Acetazolamide is

Case discussion The patient is suffering from multiple myeloma. Multiple myelomas represent a malignant proliferation of plasma cells derived from a single clone. The plasma cells in a normal individual are end-stage cells that secrete specific antibodies for a few days and then die. In contrast, the plasma cells in an individual with multiple myeloma

A 48-year-old man presents with a short history of severe low backache, loss of weight and diminished appetite. X-Ray skull shows punched out lesions. Serum electrophoresis reveals an abnormal band between the β globulin and the γ globulin region. What is the probable diagnosis? Please check the answer at: Image challenge-1- Answer