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Explanations of Quiz on Nucleotide Metabolism
- November 23, 2024
- Posted by: Namrata Chhabra
- Category: Metabolis of Nucleotides Metabolism of Nucleotides Multiple-choice questions Multiple-choice questions Mutiple-choice questions Practice questions Practice questions Quizzes USMLE Content USMLE Style questions USMLE styled question bank
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Enzymatic defects in purine and pyrimidine metabolism can present with diverse clinical features, including failure to thrive, megaloblastic anemia, hyperuricemia, or hyperammonemia. Key disorders include UMP synthase deficiency (orotic aciduria), OTC deficiency, ADA deficiency leading to SCID, and Lesch-Nyhan syndrome. Regulation through feedback inhibition and enzyme targets like ribonucleotide reductase are essential concepts for understanding metabolism and clinical interventions.
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Author:Namrata Chhabra

With over 38 years of experience as a Medical Educator, Medical Biochemist, and Researcher, Dr. Namrata Chhabra has a proven track record of leading and contributing to clinical, academic, and research initiatives that advance medical science and education. She holds an M.B.B.S., an M.D. and Ph.D. in Medical Biochemistry, and a Master's in Health Professions Education (MHPE). She is also a FAIMER Fellow, a prestigious recognition of her excellence in medical education and research.
Currently, she serves as the Associate Dean of Admissions, Chair of the Admissions Committee, and a Professor of Biochemistry at the American University of Antigua College of Medicine (AUACOM). In this role, she oversees the academic quality, curriculum development, faculty development, accreditation processes of the college, and student recruitment. She also teaches and mentors medical students, conducts and supervises biomedical and educational research projects, and publishes and presents her findings in national and international journals and conferences. Additionally, she is the author of three comprehensive textbooks on Medical Biochemistry, which are widely used by medical students and professionals. She is passionate about improving the health outcomes of communities and individuals by fostering a culture of innovation, collaboration, and excellence in medical education and research.