Burkitt’s lymphoma
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Oncogenes in Human Cancer: A Deep Dive
27
Feb

Oncogenes are key drivers of cancer, originating from proto-oncogenes that regulate normal cell functions. When mutated or overexpressed, they lead to uncontrolled cell growth and tumor formation. This article explores the molecular mechanisms of oncogene activation, including point mutations, gene amplification, chromosomal rearrangements, and viral insertional mutagenesis. Understanding these pathways has paved the way for targeted cancer treatments, offering new hope in oncology research and patient care.
Tags:
Burkitt's lymphoma,
cancer genetics,
Cancer research,
cancer treatment,
chromosomal translocation,
gene amplification,
Imatinib,
insertional mutagenesis,
molecular oncology,
oncogenes,
Philadelphia chromosome,
proto-oncogenes,
Ras activation,
targeted therapy,
tumor formation,
tumor suppressor genes,
DNA Damage And Repair
02
Feb

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Learning resources ,
Lecture notes ,
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Molecular Biology ,
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Tags:
Ataxia telangiectasia,
B-cell leukemia,
base excision repair,
Bloom syndrome,
Burkitt's lymphoma,
Cockayne's syndrome,
direct joining,
DNA repair,
double-strand break repair,
Homologous Recombination,
mismatch repair,
Nonhomologous End-Joining (NHEJ,
nucleotide excision repair,
Philadelphia chromosome,
Progeria (Hutchinson-Gilford Progeria syndrome),
Rothmund-Thomson syndrome,
Single-Strand Breaks (SSBs),
Transcription-Coupled NER,
Trichothiodystrophy,
Werner syndrome,
xeroderma pigmentosum,
Oncogenes- lecture-3
05
Dec