Cancer research
Oncogenes in Human Cancer: A Deep Dive
Oncogenes are key drivers of cancer, originating from proto-oncogenes that regulate normal cell functions. When mutated or overexpressed, they lead to uncontrolled cell growth and tumor formation. This article explores the molecular mechanisms of oncogene activation, including point mutations, gene amplification, chromosomal rearrangements, and viral insertional mutagenesis. Understanding these pathways has paved the way for targeted cancer treatments, offering new hope in oncology research and patient care.
Cancer Development: Cellular Characteristics and Carcinogenic Factors
Cancer is a disease characterized by uncontrolled cell growth, invasion of local tissues, and the ability to metastasize to distant organs. This article explores the properties of cancer cells, including loss of apoptosis, metabolic reprogramming, and genetic instability. It also examines the etiology of carcinogenesis, focusing on radiation, chemical carcinogens, and viral oncogenesis. Understanding these mechanisms is crucial for cancer prevention and treatment strategies