With 21 questions, in this section, you’ll explore real-world applications of biochemistry, sharpen your critical thinking, and connect biochemical concepts to clinical insights. Dive in, think deeply, and discover the fascinating intricacies of metabolic pathways. 1. A 35-year-old factory worker is brought to the emergency department after accidental exposure to cyanide fumes. The patient presents […]
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Through hypothetical clinical cases and research scenarios, this activity will challenge your understanding of carbohydrate metabolism, amino acid metabolism, oxidative phosphorylation, and enzymes. With 25 questions, in this section, you’ll explore real-world applications of biochemistry, sharpen your critical thinking, and connect biochemical concepts to clinical insights. Dive in, think deeply, and discover the fascinating intricacies
Biochemistry Challenge- Part 1 Read More »
1. A 2-year-old child presents to the clinic with failure to thrive and megaloblastic anemia. Laboratory tests reveal elevated urinary orotic acid levels but normal ammonia levels, normal CSF glutamine levels, and normal serum vitamin B12 and folate levels. Which enzyme deficiency is the most likely cause of this child’s condition? A. Adenosine deaminase B.
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1. In adipose tissue, through which of the following intermediates can glucose be converted to glycerol-3-phosphate for the esterification of fatty acids to form triglycerides? A. Acetyl CoA B. Dihydroxyacetone phosphate C. Glycerol D. Malate E. Pyruvate Correct Answer: B. Dihydroxyacetone phosphate: Explanation: Dihydroxyacetone phosphate (DHAP), derived from glycolysis, is reduced to glycerol-3-phosphate by the
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Question 1: What is the definition of a single-gene disorder? Answer: Single-gene disorders are genetic conditions caused by mutations in a single gene. They can follow autosomal dominant, autosomal recessive, or X-linked inheritance patterns. Question 2: Name two examples of autosomal dominant single-gene disorders. Answer: Examples include Huntington’s disease and Marfan syndrome. Question 3: What
Question 1: A 3-month-old male infant presents with delayed motor development and orange, sand-like crystals in his diaper. His parents report he constantly chews on his fingers and lips, causing bleeding. Based on these symptoms, what is the most likely diagnosis? A. Adenosine deaminase deficiency B. Gouty arthritis C. Lesch-Nyhan Syndrome D. Orotic aciduria E.
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1. An exclusively breast-fed infant presents with vomiting, weight loss, jaundice, hepatomegaly, and bilateral cataracts. Which condition is most likely responsible for these symptoms? A. Breast milk jaundice B. Classical Galactosemia C. Hereditary fructose intolerance D. Type 1 Diabetes mellitus E. Von Gierke’s disease Correct Answer: B. Classical Galactosemia Explanation: Classical galactosemia is a rare
Fructose and Galactose metabolism- Multiple-choice questions with explanations Read More »
Q.1 – Which of the following is a common compound shared by the TCA (Tricarboxylic Acid) cycle and the Urea cycle? A. α-Ketoglutarate B. Succinyl-CoA C. Oxaloacetate D. Fumarate E. Citrate Correct Answer: D. Fumarate Explanation: Fumarate is a key intermediate shared between the TCA and Urea cycles. In the Urea cycle, fumarate is produced
Amino Acid Metabolism-Multiple-Choice Questions- Set 1 Read More »
1. A 45-year-old patient presents to the clinic with significant weight loss and fatigue. Blood tests reveal elevated levels of epinephrine and glucagon. Given this clinical context, when these hormones bind to receptors on the adipose cell membrane, which of the following is NOT expected to occur? A. Fatty acids are activated, enter the mitochondria,
Fatty acid metabolism – Case-based multiple-choice questions-set 2 Read More »
1. Which of the following TCA cycle intermediates plays a crucial role in de novo fatty acid synthesis by providing substrate and positively regulating the rate-limiting enzyme involved in fatty acid synthesis? A. Citrate B. Isocitrate C. Malate D. Oxaloacetate E. Succinate Correct Answer: A. Citrate. Citrate plays a crucial role in de novo
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